HIV/AIDS: Update for Health Care Workers

10/9/01


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Table of Contents

HIV/AIDS: Update for Health Care Workers

HIV / AIDS

What is HIV ?

What is AIDS ?

Schematic of HIV

Schematic of T cell being attacked by HIV virus

Clinical Stages of HIV Infection

Primary - Acute Stage

Asymptomatic Stage

AIDS Related Complex Stage

AIDS Stage

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The course of HIV/AIDS

HIV/AIDS Factors affecting progression

Opportunistic Infections

CMV retinitis

Pneumocystis pneumonia

MALIGNANCIES IN AIDS

Kaposi’s sarcoma

Primary brain lymphoma

Wasting Syndrome

Tuberculosis in HIV and AIDS Patients

HIV and AIDS Infection in Women

HIV / AIDS Infection in Children

Neurological Abnormalities in AIDS Dementia

ANTIRETROVIRAL DRUGS AND THERAPY

Antiviral Therapy Objectives

ANTIRETROVIRAL THERAPY The moving target

Drug Treatment of HIV/AIDS

Treatment of HIV / AIDS in Pregnant Women

ANTIRETROVIRAL DRUGS Nucleoside analogs

ANTIRETROVIRAL DRUGS Protease inhibitors

HIV therapy The changing paradigm

Treating primary HIV

How to define failure

Assisting adherence

Drug toxicities

Prophylaxis of opportunistic infections

Living with HIV / AIDS

Epidemiology of HIV / AIDS

HIV: The 4th Decade

AIDS is Present in Virtually Every Country in the World

Worldwide Summary of the HIV/AIDS Epidemic, December 2000

States Reporting Highest Number AIDS Cases in USA Data as of October 2000

AIDS Cases Reported in Florida through 1999 in Seniors ( > 50 years old)

In 1995 Total AIDS Deaths Declined for the First Time

You Are Never Too Old for Sex, But You May Be Too Young To Start

Every Year 3 Million Teens Acquire a Sexually Transmitted Disease

53% of All Sexually Active High School Students Used a Condom the Last Time They Had Sex

In Choosing Your Actions You Accept the Consequences

40% of Men and 58% of Women have had an STD diagnosis at some point in their lives

Florida is SECOND in the US in reported cases of AIDS in women and children.

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In 1999 23% of Florida TB Cases were HIV Positive

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HIV Testing

HIV TESTING

HIV Culture

HIV Antibody Testing

EIA/ELISA: Used as a Screening Test Since 1985

HIV IFA Testing: Used as a confirmatory test

Western Blot: Confirmatory Test

HIV Antigen Testing

HIV Antigen p24 Testing: Diagnostic Test used in Blood Banks since 1995

HIV RNA and DNA by PCR Diagnostic test

Interpretation of HIV Results

Blood Bank Screening for HIV

Risk of HIV associated with Blood Transfusions

Incidence of AIDS associated with blood transfusion in USA since 1985

RAPID TESTS

Legal Requirements associated with HIV in Florida

Informed Consent

Exceptions to Informed Consent

Exceptions to Informed Consent Post Exposure Testing

Significant Exposure

Pre-test Counseling

Post Test Counseling: Opportunity for Face to Face Counseling The rule leaves specific post-test counseling procedures to the individual medical practice.

Release of Results

Mandatory Offering of Testing to Pregnant Females

All HIV Positive Results are Reportable as of July 1997

Partner Notification

HIV Education

Non-Discrimination

Personal Protection

HIV Transmission

Risk Categories

Options Available For Personal Protection

Safer Sex Methods

When Using A Condom Remember To:

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Female Condoms

Protection During Oral SEX

Other Personal Protection Measures:

HIV in Older People

Steps to Reduce Risk of Vertical Transmission from Infected Mother to Infant

Steps to Reduce Postpartum Transmission From Mother to Infant

Transmission of HIV Through Blood Products

HIV Transmission via Organ Transplantation

HIV and AIDS

OCCUPATIONAL EXPOSURE TO HIV

HIV Transmission

Bloodborne Pathogens Exposure Control Plan

Bloodborne Pathogen Exposure Control Plan Standard Universal Precautions

Personal Protective Equipment

Engineering Controls

Be Careful with Sharps!

Work Practice Controls

HANDWASHING RECOMMENDATIONS

HANDWASHING FOR PATIENT CARE

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Bloodborne Pathogens Exposure Facts

Potential for Transmission of Bloodborne Pathogens to Healthcare Workers

United States Healthcare Workers with Documented Occupationally Acquired HIV --1980- June, 2000

Occupationally Acquired HIV Infection in the US

HIV Post-exposure Conversion Factors

What should I do if an exposure occurs?

If it is wet and sticky and not yours,

HIV and AIDS Related Organizations, Hot lines and Resources

References:

Author: CHARLENE W. RUSE

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